Protein Purification
MilliporeSigma™ Calbiochem™ Sphingosine Kinase 1 Inhibitor, SKI-178
A cell-permeable pyrazolocarbohydrazide compound that acts as a potent, reversible, sphingosine competitive and ATP-non-competitive inhibitor of sphingosine kinase 1 (SphK1) activity with excellent selectivity over SphK2 (Ki
MilliporeSigma™ Calbiochem™ Ischemin
A cell-permeable azobenzene compound that reversibly targets CBP-BRD acetyl-lysine binding pocket with moderate selectivity over BAZ1B, PCAF, BRD4-1 and BAZ2B.
MilliporeSigma™ Calbiochem™ BLM Helicase Inhibitor, ML216
A cell-permeable pyridinyl-thiadiazolylurea compound that selectively blocks Bloom's syndrome protein (BLM) helicase activity of both full-length as well as truncated BLM636-1298 forms (IC50
MilliporeSigma™ Calbiochem™ Sphingosine Kinase-2 Inhibitor, K145
A cell permeable, selective, sphingosine competitive inhibitor of spingosine Kinase -2 (IC50 = 4.3 μM).
MilliporeSigma™ Calbiochem™ Neurotrophin Antagonist, Y1036
The Neurotrophin Antagonist, Y1036 controls the biological activity of Neurotrophin. This small molecule/inhibitor is primarily used for Neuroscience applications.
MilliporeSigma™ Calbiochem™ GSK-3 Inhibitor IX, Control, MeBIO
The GSK-3 Inhibitor IX, Control, MeBIO, also referenced under CAS 710323-61-8, controls the biological activity of GSK-3. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ SU11652
A cell-permeable pyrrole-indolinone compound that acts as a potent, reversible, and ATP-competitive tyrosine kinase receptor and angiogenic inhibitor.
MilliporeSigma™ Calbiochem™ Benztropine
An antagonist of muscarinic M1 and M3 receptors that induces robust differentiation of oligodendrocytes precursor cell differentiation (EC50 = 500nM) and promotes myelination.
MilliporeSigma™ Calbiochem™ Caspase-3 Substrate II, Fluorogenic
Fluorogenic caspase-3 substrate.
MilliporeSigma™ Calbiochem™ MitoBloCK-6
A cell-permeable, stable dichlorosalicylaldehyde Schiff's base that acts as a potent, selective inhibitor of Mia40/Erv1 redox-mediated import pathway (IC50 = 700 nM, 900 nM, an
MilliporeSigma™ Calbiochem™ PP1 Analog III, 3-MB-PP1
PP1 Analog III, 3-MB-PP1 primarily used in Inhibition.
MilliporeSigma™ Calbiochem™ L-165,041
A cell-permeable phenoxyacetic acid derivative that acts as a potent and selective peroxisome proliferator activator receptor δ (PPARδ) agonist (Ki = 6 nM for hPPARδ and 730 nM for hPPARγ).
MilliporeSigma™ Calbiochem™ FtsZ Polymer Stabilizer, PC190723
A benzamide ether derivative that exhibits potent bactericidal activity against Staphylococcus aureus and Bacillus subtilis (minimum inhibitory concentration = 0.5 to 1mg/ml), but does not affect
MilliporeSigma™ Calbiochem™ InSolution™ MG-132 in EtOH, ≥95% by HPLC
Potent, reversible, and cell-permeable proteasome inhibitor. Reduces the degradation of ubiquitin-conjugated proteins in mammalian cells and permeable stains of yeast by the 26S complex.
MilliporeSigma™ Calbiochem™ KB-R7943
A cell-permeable isothiourea derivative that inhibits the influx/reverse mode of Na+/Ca2+ exchangers (NCX; IC50